Title : Role of Machine Learning in Computational Toxicity Prediction

Authors : Ankur Omer

It is necessary to do study on how to predict toxicity since actually conducting toxicity testing may be both time-consuming and expensive. Bioinformatics tools can save time and money. Ever since its start, it has consistently delivered results. The process of analysing and classifying data is an essential component of bioinformatics. Because of their speed and low cost, in silico approaches have gained popularity in recent years for evaluating the kinetic and toxic behaviour of drugs. Machine learning is a potent tool for exploring in vitro and in vivo data for previously undiscovered complicated combinatorial associations. It has found useful applications in areas as varied as predicting pharmacodynamic characteristics and protein activities, identifying spam, locating oil spills, and recognising human voices. Algorithms such as Support Vector Machines (SVMs), Artificial Neural Networks (ANNs), and Self Organizing Maps (SOMs), as well as the difficulties they present, the potential ties they may one day forge, and the web-based toxicity prediction tools have been discussed in this article.

Keywords : Machine learning , Predictive toxicology , SVM , ANN , SOM , Toxicity prediction , in silico

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Title : 5α-dihydrotestosterone (DHT) Inhibits Tumor Necrosis Factor - alpha (TNF-α) Induced Janus Kinase-1 (JNK-1) Activation and Apoptosis in Breast Cancer in p21 Dependent Manner

Authors : Karan Singh Saini , Vijay Turkar,Rituraj Konwar

Beside established primary reproductive functions, the male hormone androgen act as a growth and survival factor for most of its target tissues. Though male androgenic hormones are widely studied, still some aspects of underlying mechanisms are not completely clear. In addition to their influence on female reproductive hormones which are considered to be crucial factor in breast carcinogenesis, several reports shows that male androgenic hormones may have direct influences on breast cancer tissues. Here, we have used dihydrosterone as model of male androgen to understand its impact on some major molecular circuitry and their by in the process of breast carcinogenesis. We observed that DHT convincingly inhibits tumor necrosis factor-alpha (TNF-α) induced Janus Kinase-1 (JNK-1) activation and apoptosis in breast cancer cells, MCF-7 in p21 dependent manner. Inhibition by androgen requires the transcription activity of androgen receptor (AR) and de novo protein synthesis. AndrogenAR induces expression of p21 that in turn inhibits tumor necrosis factor-α induced JNK activation and apoptosis. Our results reveal a novel cross-talk between AR and JNK in breast cancer (MCF-7) cells, thereby providing a molecular mechanism underlying the survival function of androgen on its target tissues or organ.

Keywords : Tumor Necrosis Factor - alpha (TNF-á) , Janus Kinase-1 (JNK-1) , Breast cancer , Apoptosis

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Title : Capture time of carriers and photons density in quantum spin lasers

Authors : seyede nasrin hosseinimotlagh,simin avazzadeh

Here we describe the structure of two types of quantum spin laser form type quantum dots and wells according to the bucket model. Then, with according to the structures, we study the laser equations first in the conventional state, then we propagate the spin state to better gain. That is, carriers and photons density, with according to the optical gain in both the conventional and spin states, is ratio to time. In the end, we examine the system in a steady state for a state not captured (τ_c=0ps) and after passing (τ_c=2ps), which is captured and photons produced.

Keywords : capture time , photons density , quantum spin lasers

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Title : Prevalence of metabolic syndrome and its association with type 2 diabetes in south Indian patients

Authors : Drala Srinivasa Rao,Pravesh Verma,Nancy Jennifer,Prathapavarma Digala,Carol Pereira

Metabolic syndrome is describes as a clustering of cardiovascular risk factors, such as, abdominal obesity, dyslipidemia, hyperglycaemia and hypertension. There are so many risk factors are common in Type 2 diabetes and cardiovascular disease, and many of these risk factors are highly correlated with one another. The risk factors of the metabolic syndrome are of metabolic origin and composed of atherogenic dyslipidemia, high plasma glucose level, elevated blood pressure, a prothrombotic state, and a pro inflammatory state. The management of persons with metabolic syndrome should have to focus not only on blood glucose control but also includes approaches for reduction of other cardiovascular disease risk factors. The present study aims to understand the prevalence of metabolic syndrome and its association with type 2 diabetes. The study group included 150 type 2 diabetes patients in the age group ranging between 20-80 years. Waist and hip circumference, BMI, Blood pressure, fasting blood glucose and Cholesterol tests like HDL and Triglycerides was determined. Prevalence of individual risk factor for metabolic syndrome was determined out of 150 patients and 97 patients were observed with high blood pressure, 85 patients were observed with low levels of HDL, 60 patients were observed with central obesity, 45 patients were observed with high triglycerides and all 150 patients were observed with diabetes.

Keywords : Metabolic Syndrome , insulin resistance , Abdominal obesity , cytokines , type 2 diabetes

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Title : Cancer Systems Biology & Epidemiology: Application in Target Identification, Combinatorial Drug Therapy & Personalized Medicine

Authors : Navneet Kumar Yadav,Ankur Omer,Poonam Singh,R. K. Singh

Cancer-signalling networks are typically complex which involves gene regulation, signalling, cell metabolism, and the alterations in its dynamics caused by the several different types of mutations leading to malignancy. Computational model of networks make possible to understand the complex behaviour of cancer-signalling network. Correlation between complexity (clustering coefficient) of cancer-signalling network pathway and Cancer Epidemiological data sets (Cancer incidence, Death rate and lifetime risk of cancer) has been validated. Results of study support the initial assumption, that the complexity of network matrices is a direct indicator of cancer threat. Understanding the differential behaviour of regulatory networks during health, disease and in response to drugs play a crucial role to enhance drug development efforts, new target identification, delineation of off-target effects, methods of disease prediction, combinatorial drug regimens and also in development of molecularly targeted personalized treatment.

Keywords : Cancer Epidemiology , clustering coefficient , Betweenness centrality , Combinatorial Drug Therapy , Personalized Medicine , Network biology

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Title : Anti-inflammatory plants: an elementary review

Authors : Pravesh Verma,Apoorva Tiwari,Rishabh Sharma,Neeraj Kumar

The inflammatory action is described as a chain of events that arise in response to noxious stimuli, infection or trauma. Various botanical species and plant parts comprise a diverse array of polyphenolic non-steroidal phytochemicals that are incorporated as floral pigments for the attraction of insects as their pollination. Various autoimmune disorders are defined by distinct inflammation and associated failure of the repair process. Pro-inflammatory molecules like TNF, certain interleukins, prostaglandins and even pathogenic concentration of nitric oxide are instrumental in raising such response. More interestingly, nitric oxide has been shown to have the ability to stimulate COX-2 showing a potential synergism. Bryophyllum pinnatum commonly known in some parts of Africa as “good luck” or “resurrection plant”, often used as an herbal remedy for human disorders, including: hypertension, diabetes mellitus, rheumatism, joint pains, insect bites, arthritis, bruises, wounds, boils, abscesses, headaches, and body pains. The leaves are also used for inguinal lymphadenitis and ear diseases. Rue contains different active compounds, out of them rutin, a flavonoid, is known to have nitric oxide scavenging activity.

Keywords : Anti-inflammatory , interleukins , TNF , COX-2 , Cytokines

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Title : Experimental study of the mechanical characteristics of mortars produced with a binder containing two cow dung ashes

Authors : Ernesto Cabral Houehanou,Marx Ferdinand Ahlinhan,Emmanuel Timothée Olodo,Gérard Léopold Gbaguidi-Aisse,Gérard Degan

This study concerns the evaluation of the mechanical characteristics of five mortars produced with a binder containing different proportions of cow dung ash produced in laboratory with objective to its using as additional mineral in the production of mortars. Five other mortars are produced with the same binder containing the same proportions cow dung ash produced traditionally and a standard mortar (control) is also produced with the same binder without any mineral in addition. Some compressive strength tests are carried out on test specimens of mortar (40x40x160 mm3 ). The compressive strength and chemical characteristic allowed us to estimate and to compare the mechanical characteristics and the pozzolanic activity ratio of both used ashes. The pozzolanic activity ratio of both types of cow dung ash is estimated to 75% and 68% in 28 days. The mechanical characteristics of the mortars containing some cow dung ash produced in laboratory are superior for the greater part to those of the mortars containing some cow dung ash produced traditionally. On the other hand, the medium-term (56 and 90 days) mechanical characteristics of the mortars containing until 15 % of cow dung ash produced in laboratory are equivalent to those of reference mortar.

Keywords : cow dung ash , additional mineral , mechanical characteristics , pozzolanic activity

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Title : Build very simple design and cost effective Geiger-Muller counter

Authors : Newaz Morshed Remon,Captain Md. Tanjir Hassan,Md. Shamim Hassan,Md. Ghulam Zakir

This paper describes our first undergraduate project experience, final report and findings on the subject matter. Initially according to our project title, we were focused on developing a low cost detector which can detect radiation only. To make one of these kinds of detector doesn't take much and can be prepared at fairly low cost being very common project in nuclear science arena. The Geiger-Muller tube, or GM tube, is an extremely useful and inexpensive way to detect radiation. While the GM tube can only detect the presence and intensity of radiation, this is often all that is needed.

Keywords : :.Introduction , Statement of Problem , Objectives , Plan of action , Technical specification , Theoretical Overview , Hypothesis , Procedure , Geiger Bot Compatibility , Application , Discussion , conclusion , Acknowledgment , References

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Title : Effect of salinity on some morphophysiological characters of somatic embryogenesis-regenerated plants of pineapple [Ananas comosus (L.) Merr. cv. Smooth Cayenne]

Authors : Kouadio Oi Kouadio Samuel,Yapo Edwige Sopie Salomé,Coulibaly Souleymane,Kouakou Tanoh Hilaire

Pineapple in Côte d'Ivoire is going through problems of various origins. Reviving this state imperatively requires both to clean up the plant material and to select varieties which easily adapt to the current pedoclimatic conditions of growing areas. This work assesses the impact of salinity on regenerated pineapple plants by somatic embryogenesis. The tests were carried out in polyethylene bags filled with sea sand, under semi-controlled conditions. Regenerated pineapple plants were watered with six saline solutions (2, 4, 6, 8, 10 and 14 g/L). Control plants were watered with water. The results revealed that salt stress reduces the studied morphophysiological parameters (number of leaves and roots, length of leaves and roots, chlorophyll a, chlorophyll b and total chlorophyll content, the carotenoids content and the relative water content). Pineapple tolerates low salt levels (2 and 4 g/L). However, important disturbances were observed in the metabolism of stressed plants with high levels of NaCl (6 and 10 g/L). As an adaptation strategy to maintain its metabolism from this stress, pineapple responded by accumulating proline. The highest saline content (14 g/L) was found to be lethal for pineapple plants.

Keywords : Acclimation , Ananas comosus , pineapple , sodium chloride , smooth cayenne

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Title : i AMF – Centralized database of arbuscular mycorrhizal distribution, phylogeny and taxonomy

Authors : Manju M. Gupta,Nikhat Naqvi,Prabhat Kumar

Arbuscular mycorrhizal fungal database, named iAMF (www.amfungi.aurobindo.du.ac.in) is first digital database on biodiversity and phylogeny of these beneficial fungi in India. It provides access to data on 161 species of arbuscular mycorrhizal fungi (AMF) along with comprehensive information on their GPS location of reported occurrence, taxonomy, molecular sequence, phylogeny and bibliography. The database is based on primary data collected by authors through ongoing surveys (year 2009-2017) and secondary data from earlier studies (2008–2016). Data is carefully curated to verify that it corresponds to the reference publication and a valid species name is used. Apart from being ecological meta-analysis data source, it would have significant application in selection of non-indigenous AMF inoculum in agriculture, reforestation, horticultural and land reclamation practices.

Keywords : AM fungi , database , arbuscular , phpMiniAdmin

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Submit a Manuscript.

1	Thomson Reuters (Clarivate Analytics)Web of Science Impact Factor 2012 : 0.5
2	NCBI-NLM Catalog, NLM ID: 101589425	https://www.ncbi.nlm.nih.gov/nlmcatalog/101589425
3	Library of Congress, USA. LCCN:89659602	https://catalog.loc.gov/vwebv/holdingsInfo?searchId=1881&recPointer=0&recCount=25&searchType=0&bibId=11363764
4	CAS (Chemical Abstracts Service is a division of the American Chemical Society) Coden: JRAAEK
5	EBSCOhost database
6	Google Scholar
7	Index Copernicus Value (ICV) 2015: 22.40
8	UGC LISTED (UGC Listed Journal No : 46213) Indexed upto 2018
9	LIVIVO	https://www.livivo.de/
10	German Union Catalogue of Serials (ZDB)	https://zdb-katalog.de/title.xhtml?idn=010504281&view=full
11	Open J-Gate
12	International Committee of Medical Journal Editors (ICMJE)	https://www.nlm.nih.gov/bsd/uniform_requirements.html
13	ResearchBib	https://journalseeker.researchbib.com/view/issn/0970-1990
14	Scientific Information Database (SID), Iran	https://www.sid.ir/en/journal/JournalList.aspx?ID=22767
15	hbz union database, Germany	http://193.30.112.134/F?func=find-c&ccl_term=IDN%3DHT007439212

	INDEXING IN UNIVESITY LIBRARIES
Sr. No.	Name of University	Address of University
1.	British University in Dubai	Dubai International Academic City, 345015 United Arab Emirates
2.	Abu Dhabi University	Abu Dhabi, 59911 United Arab Emirates
3.	Technische Informationsbibliothek (TIB) / Leibniz-Informationszentrum Technik und Naturwissenschaften und Universitätsbibliothek	TIB Hannover Hannover, 30167 Germany
4.	Universitätsbibliothek J. C. Senckenberg, Zentralbibliothek (ZB)	Frankfurt/Main, 60325 Germany
5.	The British Library, On Demand	Wetherby, West Yorkshire, LS23 7BQ United Kingdom
6.	The British Library, St. Pancras	London, NW1 2DB United Kingdom
7.	University of Edinburgh - Main Library	Edinburgh, EH8 9LJ United Kingdom
8.	University of Liverpool, Sydney Jones Library	Liverpool, L69 3DA United Kingdom
9.	CSIR Information Services	Pretoria, 0001 South Africa
10.	University of the Witwatersrand Library	Johannesburg, 2001 South Africa
11.	Botswana International University of Science & Technology	Palapye, Botswana
12.	University of Cape Town Libraries	Cape Town, 7700 South Africa
13.	Charles Sturt University	Bathurst NSW, 2795 Australia
14.	Melbourne Institute of Technology (MIT)	Melbourne, AU-VI 3000 Australia
15.	Southern Cross University	Lismore, NSW 2480 Australia
16.	Torrens University	Fitzroy, AU-VI 3065 Australia
17.	University of Canberra Library	Canberra Act, AU-CT 2616 Australia
18.	Bibliothèque de l'Université du Québec à Rimouski	Rimouski, QC G5L 3A1 Canada
19.	Université du Québec à Chicoutimi	Chicoutimi, QC G7H 2B1 Canada
20.	University of Washington Libraries	Seattle, WA 98195 United States
21.	Université Laval, Bibliothèque	Québec, QC G1V 0A6 Canada
22.	Bibliothèque HEC Montréal	Montreal, QC H3T 2A7 Canada
23.	Bibliothèque de l'Université du Québec à Trois-Rivières	Trois-Rivières, QC G8Z 4M3 Canada
24.	Bishop's University Library Learning Commons	Sherbrooke, QC J1M 1Z7 Canada
25.	Concordia University Library	Montreal, QC H3G 1M8 Canada
26.	Université de Sherbrooke - Service des bibliothèques et archives	Sherbrooke, QC J1K 2R1 Canada
27.	Université du Québec en Abitibi-Témiscamingue	Rouyn-Noranda, QC J9X 5E5 Canada
28.	Université du Québec à Montréal	Montreal, QC H2L 4Y2 Canada
29.	cole nationale d'administration publique	Montréal, QC H2T 3E5 Canad
30.	Université du Québec en Outaouais	Gatineau, QC J8X 3X7 Canada
31.	Concordia College Library	Moorhead, MN 56562 United States
32.	Fitchburg State University	Fitchburg, MA 01420 United States
33.	Mohawk Valley Community College	Utica, NY 13501 United States
34.	Rensselaer Polytechnic Institute	Troy, NY 12180 United States
35.	University at Albany	Albany, NY 12222 United States
36.	Augsburg University	Minneapolis, MN 55454 United States
37.	Buffalo State - SUNY College at Buffalo	Buffalo, NY 14222 United States
38.	Central Connecticut State University	New Britain, CT 06050 United States
39.	City College / CUNY	New York, NY 10031 United States
40.	Lehman College Library	Bronx, NY 10468 United States
41.	Manhattan College	Bronx, NY 10471 United States
42.	Mansfield University of Pennsylvania	Mansfield, PA 16933 United States
43.	New York Institute of Tech	Old Westbury, NY 11568 United States
44.	Saginaw Valley State University, Zahnow	University Center, MI 48710 United States
45.	Bloomsburg University	Bloomsburg, PA 17815 United States
46.	Brooklyn College	Brooklyn, NY 11210 United States
47.	CUNY Craig Newmark Graduate School of Journalism	New York, NY 10018 United States
48.	CUNY The Graduate Center Library	New York, NY 10016 United State
49.	City University of New York	New York, NY 10021 United States
50.	Cleveland State University Library	Cleveland, OH 44115 United States
51.	College of Staten Island, CUNY	Staten Island, NY 10314 United States
52.	GM Library	Warren, MI 48092 United States
53.	Hunter College	Jacqueline Grennan Wexler Library New York, NY 10021 United States
54.	Idaho State University Library	Eli M.Oboler Library Pocatello, ID 83209 United States
55.	John Jay College of Criminal Justice Library	Lloyd George Sealy Library New York, NY 10019 United States
56.	Kalamazoo Valley Community College Library	Texas Township Campus Library Kalamazoo, MI 49003 United States
57.	Kingsborough Community College	Robert J. Kibbee Library Brooklyn, NY 11235 United States
58.	LaGuardia Community College Library Media Resources Center	Library Media Resources Center, Long Island City, NY 11101 United States
59.	Lawrence Technological University	Lawrence Tech; LTU Southfield, MI 48075 United States
60.	Martin Luther College	MLC Library New Ulm, MN 56073 United States
61.	Medgar Evers College	Charles Evans Inniss Memorial Library Brooklyn, NY 11225 United States
62.	Muskegon Community College	Hendrik Meijer Library Muskegon, MI 49442 United States
63.	Queens College	Benjamin Rosenthal Library Flushing, NY 11367 United State
64.	Spring Arbor University	Hugh A. and Edna C. White Library Spring Arbor, MI 49283 United States
65.	University of Auckland, General Library	Auckland, 1010 New Zealand
66.	University of Canterbury, Central Library	Christchurch, 8041 New Zealand
67.	University of Michigan	Ann Arbor, MI 48109 United States
68.	University of Sioux Falls	Mears Library Sioux Falls, SD 57105 United States
69.	Western Theological Seminary	Cook Library Holland, MI 49423 United States
70.	Beloit College Library	Beloit, WI 53511 United States
71.	Center for Research Libraries	Chicago, IL 60637 United States
72.	Divine Mercy University	Mary S. Thelen Library Sterling, VA 20166 United States
73.	George Mason University	Fenwick Library Fairfax, VA 22030 United States
74.	Hillsdale College, Mossey Library	Mossey Library, Hillsdale College Hillsdale, MI 49242 United States
75.	Institute for Defense Analyses Library	Alexandria, VA 22311 United States
76.	Iowa State University	Ames, IA 50011 United States
77.	Laurel Ridge Community College Learning Resource Center	Middletown, VA 22645 United States
78.	Marymount University	Emerson G. Reinsch Library Arlington, VA 22207 United States
79.	Shenandoah University	Alson H. Smith, Jr. Library Winchester, VA 22601 United States
80.	Shippensburg University of Pennsylvania	Shippensburg, PA 17257 United States
81.	Trine University	Sponsel Library Angola, IN 46703 United States
82.	University of Chicago Library	Chicago, IL 60637 United States
83.	Victoria University of Wellington, Kelburn Library	Wellington, 6012 New Zealand
84.	Weber State University	Stewart Library Ogden, UT 84408 United States
85.	West Virginia Northern Community College	Wheeling, WV 26003 United State
86.	West Virginia University Libraries	Morgantown, WV 26505 United States
87.	Wilmington University Library	New Castle, DE 19720 United States
88.	Youngstown State University	William F. Maag Jr. Library Youngstown, OH 44555 United States
89.	Antioch University Library	Yellow Springs, OH 45387 United States
90.	Bridgewater College	Library Services Bridgewater, VA 22812 United States
91.	Christendom College Libraries	St. John the Evangelist Library Front Royal, VA 22630 United States
92.	Eastern Virginia Medical School Library	Brickell Medical Sciences Library Norfolk, VA 23501 United States
93.	Fairmont State University	Ruth Ann Musick Library Fairmont, WV 26554 United States
94.	Grafton Library - Mary Baldwin University	Staunton, VA 24401 United States
95.	J Sargeant Reynolds Community College	Downtown Campus Library Richmond, VA 23228 United States
96.	Norfolk State University	Lyman Beecher Brooks Library Norfolk, VA 23504 United States
97.	Ohio State University Libraries	Columbus, OH 43210 United States
98.	Old Dominion University	Old Dominion University Libraries Norfolk, VA 23508 United States
99.	Randolph Macon College McGraw-Page Library	Ashland, VA 23005 United States
100.	University of Virginia	University of Virginia Libraries; University of Virginia Library; UVA Library Charlottesville, VA United States
101.	Virginia Commonwealth University	VCU Libraries Richmond, VA 23284 United States
102.	Virginia Military Institute	Preston Library Lexington, VA 24450 United States
103.	Virginia Wesleyan University	Hofheimer Library Virginia Beach, VA 23455 United States
104.	West Virginia University at Parkersburg	Parkersburg, WV 26104 United States
105.	Wilberforce-Payne Unified Library	Rembert E. Stokes Library and Information Commons / Reverdy C. Ransom Memorial Library Wilberforce, OH 45384 United States
106.	William And Mary	Williamsburg, VA 23186 United States
107.	Averett University	Blount Library Danville, VA 24541 United States
108.	Boulder Labs Library	Boulder, CO 80305 United States
109.	Hampden-Sydney College	Bortz Library Hampden-Sydney, VA 23943 United States
110.	Linda Hall Library	Kansas City, MO 64110 United States
111.	McDermott Library, USAF Academy	U.S. Air Force Academy Library USAF Academy, CO 80840 United States
112.	McKendree University	Holman Library Lebanon, IL 62254 United States
113.	Radford University Library	McConnell Library Radford, VA 24142 United States
114.	Regent University	Virginia Beach, VA 23464 United States
115.	Richard Bland College	South Prince George, VA 23805 United States
116.	Roanoke Higher Education Center	Roanoke, VA 24016 United States
117.	University of Colorado Boulder	Boulder, CO 80309 United States
118.	University of Lynchburg	Knight-Capron Library Lynchburg, VA 24501 United States
119.	Vincennes University	Shake Library Vincennes, IN 47591 United States
120.	Virginia Tech	University Libraries at Virginia Tech Blacksburg, VA 24061 United States
121.	GTCC Libraries	Guilford Technical Community College Libraries Jamestown, NC 27282 United States
122.	North Carolina A&T State University, F.D. Bluford Library	Ferdinand Douglass Bluford Library Greensboro, NC 27411 United States
123.	North Carolina State University	Raleigh, NC 27695 United States
124.	University of Evansville	Evansville, IN 47722 United States
125.	Cumberland University	Lebanon, TN 37087 United States
126.	Northern New Mexico College	Espanola Campus Library Espanola, NM 87532 United States
127.	Northwestern Oklahoma State University Library	Alva, OK 73717 United States
128.	San Juan College Library	Farmington, NM 87402 United States
129.	University of New Mexico -Taos	Ranchos de Taos, NM 87557 United States
130.	University of New Mexico, Gallup Campus	Zollinger Library Gallup, NM 87301 United States
131.	University of New Mexico, Los Alamos	Los Alamos, NM 87544 United States
132.	Atlanta University Center Robert W. Woodruff Library	Atlanta, GA 30314 United States
133.	Central New Mexico Community College Libraries	Albuquerque, NM 87106 United States
134.	Institute of American Indian Arts Library	Santa Fe, NM 87508 United States
135.	New Mexico Highlands University	Las Vegas, NM 87701 United States
136.	Oklahoma Christian University	Beam Library Edmond, OK 73013 United States
137.	Rose State College Library	Midwest City, OK 73110 United States
138.	Santa Fe Community College	Santa Fe, 87508 United States
139.	Southwestern Oklahoma State University	Al Harris Library Weatherford, OK 73096 United States
140.	University of New Mexico Valencia Campus Library	Valencia Campus Los Lunas, NM 87031 United States
141.	University of New Mexico-Main Campus	Albuquerque, NM 87131 United States
142.	Eastern New Mexico University	Golden Library Portales, NM 88130 United States
143.	Eastern New Mexico University, Roswell	Learning Resource Center Roswell, NM 88202 United States
144.	Eastern New Mexico University, Ruidoso Branch Library	Ruidoso Branch Community College Library Ruidoso, NM 88345 United States
145.	New Mexico Institute of Mining & Technology	NMT Joseph R. Skeen Library; Skeen Library; NMT Library Socorro, NM 87801 United States
146.	Saint Leo University	Daniel A. Cannon Memorial Library Saint Leo, FL 33574 United States
147.	Texas A&M University-Central Texas	A&M-Central Texas Killeen, TX 76549 United States
148.	University of South Florida	Tampa, FL 33620 United States
149.	Florida Memorial University	Nathan W. Collier Library Miami Gardens, FL 33054 United States
150.	St. Thomas University Law Library	Miami Gardens, FL 33054 United States
151.	Texas A&M University-San Antonio	San Antonio, TX 78224 United States
152.	Texas Southern University	Library Learning Center Houston, TX 77004 United States
153.	Sistema de Bibliotecas, Universidad de Puerto Rico, Recinto de Río Piedras	San Juan, PR 00931 United States
154.	Texas A&M International University	Laredo, TX 78041 United States
155.	Universidad de Puerto de Cayey	Biblioteca Victor M. Pons Gil Cayey, 00737-2230 Puerto Rico
156.	Universidad de San Andrés	Biblioteca Max von Buch Buenos Aires, 1644 Argentina
157.	Universidad de las Americas	Quito, Ecuador

Journal of Recent Advances in Applied Sciences (pISSN 0970-1990) is an open access journal. The first issue of Journal of Recent Advances in Applied Sciences was published in 1986 under the supervision of Late Prof. K.G. Mukerji, Ph.D., Department of Botany, Delhi University, Delhi, India. Journal was being successfully run and managed by succeeding editors and thus, achieved the indexing in Clarivate Analytics Science Citation Index(SCI) with an Impact Factor of 0.5 during year 2012. Journal is also indexed in NCBI-NLM Catalogue; EBSCOhost database (ebscohost.com); CAS Source Index (CASSI); German Union Catalogue of Serials (ZDB); hbz union database, Germany etc. Further, more than 150 leading Universities from USA, Germany, United Kingdom, Canada, New Zealand and South Africa have subscribed to the print issues of the journal. Our journal fulfils all guidelines for counting research publications for promotion of teaching faculty of medical colleges/institutions in India as laid down in an order by (MCI) Medical Council of India. For more details visit the abstracting and indexing page of the journal. Details of abstracting and indexing are following:

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Manuscripts are sent for peer review to independent reviewers/ academic editors. Author must have sent the list of 4-5 suggested reviewers/academic editors along with the manuscript. Criteria followed for suggested reviewers/ academic editors is as follows: They must not have from the same organisation and not have publication with the authors & co-authors of a manuscript.

Preparation of the Manuscript

Manuscript can be submitted by any of the contributing author(s). Manuscript files should be submitted only in Microsoft Word format (doc or docx).

Title and Authorship Information

The following information should be included with manuscript title

• Full author(s) name
• Affiliation(s) where the research work was carried out and institutional mailing addresses of all author(s)
• Email addresses of all author(s) including corresponding author(s)
• Mobile no. of all author(s)
• Social media links of all author(s) ( facebook, Twitter, Youtube, Instagram)

Title should be short & informative, to be typed in only the first letter of the first word capital; also, after colon or hyphen, first letter of the first word capital. Latin names are to be given in italics. Names of authors to be typed in first letters capital . Author for correspondence should be indicated with an asterisk (*).

Main Headings

Each manuscript should be divided into the following main headings (typed in bold, first letters capital, on the left hand side of the page; 12 pt):

• Abstract
• Keywords
• Introduction
• Materials and Methods
• Results
• Discussion
• Conclusions
• Conflict of Interest (if any)
• Acknowledgement (if any)
• Funding statement
• Abbreviations (if any)
• References

Sub-Headings (if any)

Typed in flush left, bold, first letters capital (12 pt).

Sub-Sub Headings (if any)

Bold-Italics, first letters capital (10 pt).

Tables

Tables should be cited consecutively in the text. Every table must have a descriptive title and if numerical measurements are given, the units should be included in the column heading. Vertical rules should not be used.

Figures

The line drawings, illustrations or photographs will be accepted in Word files, GIF, JPEG, etc. Lettering, numbering, symbols and lines in the graphs/illustrations should be sufficiently clear and large.

Reference

All references should be listed consecutively, as they appeared in the text at the end of the manuscript. Up to six authors are cited, In case of more than six authors replaced by et al. Formating of citation should be done according to "NLM '' guideline. For more details, visit the NLM website using the following link (https://www.nlm.nih.gov/bsd/uniform_requirements.html). In referencing software, NLM style should be chosen during preparation of manuscript.

In-text citation style:

In text citation should be done using numbers in square brackets. e.g., “ inflammation, and cancer [1–3].”; “ cause severe diseases [4, 5]”.

Graphical Abstract:

Each manuscript must be submitted along with a graphical abstract. It should be designed in such a way so that visual representation will be interactive along with showing scientific summary of the article.

Technical guidelines to prepare it as following:

• Have a resolution of 1280x720 (with minimum width of 640 pixels).
• Image formats should be JPG, GIF, or PNG.
• Maximum file limit.
• Use a 16:9 aspect ratio

Video of Research

Authors of each manuscript should have to prepare videos of their research work. Authors are allowed to submit upto 3 videos.

• Content of the first video must represent the scientific work of the manuscript.
• Second and third videos may be a blog or personal blog of a research lab, research institute, university, scientific team, author of manuscript. research work journey, field work etc.

Videos should be created as per technical requirement of youtube. For more details use following link https://support.google.com/youtube

Submission Preparation Checklist

• Manuscript in Microsoft Word file formats
• Tables submit in separate file
• Figures submit in separate file
• Graphical Abstract
• List of 4-5 suggested reviewers/academic editors
• Plagiarism report of manuscript by turnitin (if authors do not have plagiarism report, they submit their manuscript without it. It will be generated by us. )
• There is no need to send video at the time of submit video at the time of manuscript submission. Video will be required after initial screening of the manuscript. Separate email will be sent to authors for this purpose.

After Acceptance of Manuscript

• Authors have to send their videos to the journal.
• Before publication of manuscript, it is mandatory for all the authors to join the lifetime membership of our research society (Scientific Association of India). This membership is applicable for all the journals published by Anveshika Publishing & Informatics. A lifetime certificate is provided in softcopy and hardcopy to the members. Certificates are sent by India Post.
• Article processing charges: 5000 INR for each article published in journal.

Statement of Human and Animal Rights

In the research work where human subjects or material were involved, all authors should clearly declare that entire experiment work was done as per ethical standards of the responsible committee on human experimentation (both institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000 and 2008. In case of animal experiments, authors should clearly reveal that all experimental procedures were done according to institutional and national guidelines for animal care and laboratory use.

Statement of Informed Consent

Patients have a right to privacy that should not be infringed without informed consent. Identifying information, including patients' names, initials, or hospital numbers, should not be published in written descriptions, photographs, and pedigrees unless the information is essential for scientific purposes and the patient (or parent or guardian) provides written informed consent for publication. Authors should also identify individuals who provide writing assistance and disclose the funding source for this assistance. Identifying details should be omitted if they are not essential. Complete anonymity is difficult to achieve; however, informed consent should be obtained if there is any doubt. For example, masking the eye region in photographs of patients is inadequate to ensure anonymity. If identifying characteristics are altered to protect the patient, such as in genetic pedigrees, authors should guarantee that alterations do not distort scientific meaning.

Publication Ethics and Publication Malpractice Statement

Editor’s responsibilities

Editors are responsible for taking the decision to publish a submitted manuscript on the basis of quality, originality, scope and relevance. Editor and editorial staff will maintain the necessary confidentiality of the manuscript and will not use it for any other purpose.

Reviewer’s responsibilities

Reviewers should screen the manuscript for various quality parameters and provide the relevant comments to the editors, which helps them in decision making. Reviewers must carefully check the literature citation, writing quality, experiment setup and scientific relevance of results. A special emphasis will be given on plagiarism checking of manuscript. Reviewers will also maintain the necessary confidentiality of the manuscript and will not use it for any other purpose. Conflicts of interest regarding collaboration with authors of submitted manuscript must be disclosed to the editor, and then excluded from the review process.

Author’s responsibilities

Manuscript submitted to our journal should not be published in any other journal, and also not currently under consideration by another journal. The manuscript must be approved by all the co-authors for their scientific contents and submission for publication in the journal.

Authors should provide the details of their experimental work so that others may replicate the experiments. Authors should prepare their raw data and submit it to editors/reviewers upon request.

Any kind of fraud or unethical practices like Fabrication/ Falsification of Data, Plagiarism, Unacceptable Author Contribution, Citation Manipulation, Concurrent Submissions, and Redundant Publications are totally unacceptable. All authors must give a clear statement that no unethical practices are involved in this research work. All authors have a responsibility to disclose the conflicts of interests and financial support for work, if any.

After publication of the manuscript, if any error is found in research work, the chief-editor should be immediately informed. After deep discussion with the research team, the manuscript will be corrected or even withdrawn.

Literature source for ethical standard

• Committee on Publication Ethics (COPE). Code of Conduct and Best-Practice Guidelines for Journal Editors.
• Graf C, Wager E, Bowman A, Fiack S, Scott-Lichter D, Robinson A. Best Practice Guidelines on Publication Ethics: a publisher's perspective. Int J Clin Pract Suppl. 2007 Jan;61(152):1-26.
• International Committee of Medical Journal Editors. Uniform Requirements for Manuscripts Submitted to Biomedical Journals: Writing and Editing for Biomedical Publication. 2006.
• American Psychological Association. Ethical Principles of Psychologists and Code of Conduct, Section 8 ‘Research and Publication’.
• American Chemical Society. Ethical Guidelines.