Keratin waste is generated in large amounts from various industrious as well as a by-product of commercial poultry and leather processing units and is highly resistant to degradation by conventional proteolytic enzymes viz. Pepsin, Papain and Subtilisin. Keratinases are a particular class of proteolytic enzymes that display the capability of degrading insoluble keratin substrates by diverse microbes. In the present study we have tested the keratinolytic ability of our lab isolate Bacillus sp. Ker17 strain by using four different keratin wastes under submerged fermentation at 37 °C temperature and pH 9.0 Among different keratins added to basal medium, nails were effectively degraded about 97.9(±0.2) % within about 5.3 (±0.2) days where soluble protein produced was 37.7 ±2.0 mg/ml and protease activity exhibited at 343.1 ±0.1 U/ml. However, different keratin wastes degradation time varied from 5.3 to12.5 days. Ker17 strain can be an effective tool for the processing and or management of solid keratin litter and gives a remedy for environmental concern over abundant keratinaceous waste conversion to value added product formation in biotech industry with its promising keratinolytic abilities.